Presymptomatic Retinal Sensitivity Changes in Intermediate Age-Related Macular Degeneration Associated With New Retinal Fluid
Antony J Wightman, Carla J Abbott, Myra B McGuinness, Emily Caruso, Robyn H Guymer, Chi D Luu
Translational Vision Science & Technology | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2019
Purpose: To determine whether change in retinal sensitivity in areas with subretinal or intraretinal fluid secondary to age-related macular degeneration (AMD) precedes visual symptoms. If confirmed, retinal sensitivity testing could be used for home monitoring in AMD. Methods: Individuals with intermediate AMD enrolled in a longitudinal study were seen every 6 months and underwent best-corrected visual acuity testing (BCVA), spectral domain-optical coherence tomography (SD-OCT), and microperimetry. Asymptomatic individuals who developed incidental, reading center-determined retinal fluid detected on SD-OCT were identified. The point-wise sensitivity (PWS) at the time of fluid detection was c..View full abstract
Awarded by National Health and Medical Research Council (NHMRC) Fellowship
Awarded by NHMRC
Supported by National Health and Medical Research Council (NHMRC) Fellowship (#1103013, RHG) and NHMRC Project Grant (1084081). The Centre for Eye Research Australia (CERA) receives operational infrastructure support from the Victorian State Government.