Journal article

Adolescent tuberculosis

Kathryn J Snow, Andrea T Cruz, James A Seddon, Rashida A Ferrand, Silvia S Chiang, Jennifer A Hughes, Beate Kampmann, Steve M Graham, Peter J Dood, Rein M Houben, Justin T Denholm, Susan M Sawyer, Katharina Kranzer

The Lancet Child & Adolescent Health | Elsevier BV | Published : 2019

Abstract

Adolescence is characterised by a substantial increase in the incidence of tuberculosis, a known fact since the early 20th century. Most of the world's adolescents live in low-income and middle-income countries where tuberculosis remains common, and where they comprise a quarter of the population. Despite this, adolescents have not yet been addressed as a distinct population in tuberculosis policy or within tuberculosis treatment services, and emerging evidence suggests that current models of care do not meet their needs. This Review discusses up-to-date information about tuberculosis in adolescence, with a focus on the management of infection and disease, including HIV co-infection and rifa..

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Grants

Awarded by UK Medical Research Council under the MRC/DFID Concordat agreement


Awarded by UK Department for International Development (DFID) under the MRC/DFID Concordat agreement


Awarded by Wellcome Trust


Awarded by US National Institutes of Health


Awarded by MRC


Awarded by European Research Council under the European Union's Horizon 2020 research and innovation programme


Awarded by UK MRC


Funding Acknowledgements

KJS is supported by the Centre for Research Excellence in Tuberculosis, which is funded by the National Health and Medical Research Council of Australia. JAS is supported by a Clinician Scientist Fellowship jointly funded by the UK Medical Research Council and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement (MR/R007942/1). RAF is funded by the Wellcome Trust (grant number: 206316/Z/17/Z). SSC is supported by the US National Institutes of Health (K01TW010829). BK is funded by the MRC (MC_UP_ A900/1122, MR/K011944/1, MR/P024270/1). RMH received funding from the European Research Council under the European Union's Horizon 2020 research and innovation programme (grant number: 757699). PJD is funded by a fellowship from the UK MRC (MR/P022081/1). The funders had no role in decision to publish or preparation of the manuscript.