Journal article
Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and Hexafluoropropylene Oxide Dimer Acid (GenX) in a Benthic Fish
Kathryn L Hassell, Timothy L Coggan, Tom Cresswell, Adam Kolobaric, Kathryn Berry, Nicholas D Crosbie, Judy Blackbeard, Vincent J Pettigrove, Bradley O Clarke
Environmental Toxicology and Chemistry | Wiley | Published : 2020
DOI: 10.1002/etc.4640
Abstract
Per‐ and poly‐fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccumulate in organisms. We examined dietary uptake and depuration of a mixture of 3 PFAS: perfluorooctanoic acid (PFOA; C8HF15O2), perfluorooctane sulfonate (PFOS; C8HF17SO3), and hexafluoropropylene oxide dimer acid (HPFO‐DA; C6HF11O3; trade name GenX). Benthic fish (blue spot gobies, Pseudogobius sp.) were fed contaminated food (nominal dose 500 ng g–1) daily for a 21‐d uptake period, followed by a 42‐d depuration period. The compounds PFOA, linear‐PFOS (linear PFOS), and total PFOS (sum of linear and branched PFOS) were detected in freeze‐dried fish, whereas GenX was not, i..
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Funding Acknowledgements
The present study was funded by the Melbourne Water Corporation with additional resources provided by the Centre for Aquatic Pollution Identification and Management, the University of Melbourne, the Royal Melbourne Institute of Technology University, and the Victorian Marine Sciences Consortium. We acknowledge the support of Agilent Technologies in giving technical assistance with instrument setup and operation. We thank T. Mehler, J. Myers, M. Hoak, J. French, M. Sole, and F. Alexander for assistance with fish collections, and R. Watson, S. Krueger, N. Williamson, and S. Nie for assistance with laboratory procedures.