Journal article

Geometry of the Retinal Nerve Fibers From Emmetropia Through to High Myopia at Both the Temporal Raphe and Optic Nerve

Phillip Bedggood, Soumya Mukherjee, Bao N Nguyen, Andrew Turpin, Allison M McKendrick

Investigative Opthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2019

Abstract

Purpose: The geometry of retinal nerve fibers may be altered with myopia, a known risk factor for glaucoma. Recent developments in high resolution imaging have enabled direct visualization of nerve fiber bundles at the temporal raphe with clinical hardware, providing evidence that this area is sensitive to glaucomatous damage. Here, we test the hypothesis that nerve fiber geometry is altered by myopia, both at the temporal raphe and surrounding the optic nerve head. Methods: Seventy-eight healthy individuals participated, with refractive errors distributed between emmetropia and high myopia (+0 to -13 DS). Custom high-density OCT scans were used to visualize RFNL bundle trajectory at the tem..

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Grants

Awarded by Australian Research Council (ARC) Linkage Project


Funding Acknowledgements

Supported by Australian Research Council (ARC) Linkage Project LP13100055 funding and research support from Heidelberg Engineering GmBH, Heidelberg, Germany. The sponsor and funding organization had no role in the design or conduct of this research.