Journal article

Depression, stress and vascular function from childhood to adolescence: A longitudinal investigation

Lisa S Olive, Walter P Abhayaratna, Don Byrne, Rohan M Telford, Michael Berk, Richard D Telford

General Hospital Psychiatry | ELSEVIER SCIENCE INC | Published : 2020


BACKGROUND: Psychological distress is associated with risk markers for cardiovascular disease, including increased arterial stiffness and high blood pressure, but it's unclear when these first manifest. This study aims to investigate the effect of psychosocial stress and depression on arterial stiffness and blood pressure in a cohort study of Australian children followed through to adolescence. METHOD: Depression and psychosocial stress in 520 young people (265 boys; M age = 11.6 y) were assessed via the Children's Depression Inventory and Children's Stress Questionnaire respectively. Carotid-femoral pulse wave velocity was assessed using applanation tonometry, with further assessments of su..

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University of Melbourne Researchers


Awarded by National Heart Foundation of Australia/National Health and Medical Research Council

Funding Acknowledgements

Support for this research was provided via a co-funded National Heart Foundation of Australia ( Health and Medical Research Council ( Postgraduate Scholarship [GNT1056551] awarded to LO; an Australian Research Council Linkage Grant to DB; and from The Commonwealth Education Trust (New Zealand House, London, UK); ( awarded to DT. Adolescent work was funded by the Canberra Hospital Salaried Staff Specialists Fund awarded to WA. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.