Journal article
Optic Radiation Tractography in Pediatric Brain Surgery Applications: A Reliability and Agreement Assessment of the Tractography Method
JYM Yang, R Beare, MH Wu, SM Barton, CB Malpas, CH Yeh, AS Harvey, V Anderson, WJ Maixner, M Seal
Frontiers in Neuroscience | Published : 2019
Abstract
Background: Optic radiation (OR) tractography may help predict and reduce post-neurosurgical visual field deficits. OR tractography methods currently lack pediatric and surgical focus. Purpose: We propose a clinically feasible OR tractography strategy in a pediatric neurosurgery setting and examine its intra-rater and inter-rater reliability/agreements. Methods: Preoperative and intraoperative MRI data were obtained from six epilepsy and two brain tumor patients on 3 Tesla MRI scanners. Four raters with different clinical experience followed the proposed strategy to perform probabilistic OR tractography with manually drawing anatomical landmarks to reconstruct the OR pathway, based on fiber ..
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Awarded by Department of Pediatrics, University of Florida
Funding Acknowledgements
This research was funded by Australia's National Health and Medical Research Council (Postgraduate Scholarship 1039160 to JY; Peter Doherty Biomedical Research Fellowship to CM) and The Royal Children's Hospital Foundation (RCH1000 to SB and JY). This research was conducted within the Department of Neurosurgery, The Royal Children's Hospital, and the Developmental Imaging and Neuroscience Research Groups, Murdoch Children's Research Institute at the Melbourne Children's MRI Centre, Melbourne, Victoria. It was supported by The Royal Children's Hospital Foundation, Murdoch Children's Research Institute, The University of Melbourne, Department of Pediatrics, and the Victorian Government's Operational Infrastructure Support Program.