Pre-school child blood lead levels in a population-derived Australian birth cohort: the Barwon Infant Study
Christos Symeonides, Peter Vuillermin, Peter D Sly, Fiona Collier, Victoria Lynch, Sandra Falconer, Angela Pezic, Nicole Wardrop, Terence Dwyer, Sarath Ranganathan, Anne-Louise B Ponsonby
Medical Journal of Australia | WILEY | Published : 2019
OBJECTIVES: To investigate blood lead levels in an Australian birth cohort of children; to identify factors associated with higher lead levels. DESIGN, SETTING: Cross-sectional study within the Barwon Infant Study, a population birth cohort study in the Barwon region of Victoria (1074 infants, recruited June 2010 - June 2013). Data were adjusted for non-participation and attrition by propensity weighting. PARTICIPANTS: Blood lead was measured in 523 of 708 children appraised in the Barwon Infant Study pre-school review (mean age, 4.2 years; SD, 0.3 years). MAIN OUTCOME MEASURE: Blood lead concentration in whole blood (μg/dL). RESULTS: The median blood lead level was 0.8 μg/dL (range, 0.2-3.7..View full abstract
Awarded by National Health and Medical Research Council (NHMRC)
The Victorian Department of Health and Human Services contributed funding for the analysis of blood lead levels. The establishment and infrastructure for the Barwon Infant Study was funded by the Murdoch Children's Research Institute, Deakin University, and Barwon Health. Subsequent funding was provided by the National Health and Medical Research Council (NHMRC; grants APP607370, APP1009044, APP1029927, APP1024619, APP1030701, APP1076667, APP1147970); the Shepherd Foundation; the Jack Brockhoff Foundation; the Scobie Trust; the Shane O'Brien Memorial Asthma Foundation; the Our Women's Our Children's Fundraising Committee Barwon Health; the Rotary Club of Geelong; the Ilhan Food Allergy Foundation; Geelong Medical and Hospital Benefits Association; the Percy Baxter Charitable Trust; Perpetual Trustees; and Vanguard Investments Australia. In-kind support was provided by the Cotton On Foundation and CreativeForce. Research at the Murdoch Children's Research Institute is supported by the Victorian Government through the Operational Infrastructure Support Program. Christos Symeonides is supported by an NHMRC Postgraduate Research Scholarship. Peter Vuillermin, Peter Sly and Anne-Louise Ponsonby are supported by NHMRC Fellowships. The funding sources had no role in study design, data collection, analysis or interpretation, reporting or publication.