Angiotensin-Converting Enzyme Genetic Polymorphism: Its Impact on Cardiac Remodeling

Felipe Neves de Albuquerque; Andrea Araujo Brandao; Dayse Aparecida da Silva; Ricardo Mourilhe-Rocha; Gustavo Salgado Duque; Alyne Freitas Pereira Gondar; Luiza Maceira de Almeida Neves; Marcelo Imbroinise Bittencourt; Roberto Pozzan; Denilson Campos de Albuquerque

Journal article

Angiotensin-Converting Enzyme Genetic Polymorphism: Its Impact on Cardiac Remodeling

Felipe Neves de Albuquerque, Andrea Araujo Brandao, Dayse Aparecida da Silva, Ricardo Mourilhe-Rocha, Gustavo Salgado Duque, Alyne Freitas Pereira Gondar, Luiza Maceira de Almeida Neves, Marcelo Imbroinise Bittencourt, Roberto Pozzan, Denilson Campos de Albuquerque

ARQUIVOS BRASILEIROS DE CARDIOLOGIA | ARQUIVOS BRASILEIROS CARDIOLOGIA | Published : 2014

DOI: 10.5935/abc.20130229

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Abstract

BACKGROUND: The role of angiotensin-converting enzyme genetic polymorphisms as a predictor of echocardiographic outcomes on heart failure is yet to be established. The local profile should be identified so that the impact of those genotypes on the Brazilian population could be identified. This is the first study on exclusively non-ischemic heart failure over a follow-up longer than 5 years. OBJECTIVE: To determine the distribution of angiotensin-converting enzyme genetic polymorphism variants and their relation with echocardiographic outcome of patients with non-ischemic heart failure. METHODS: Secondary analysis of the medical records of 111 patients and identification of the angiotensin-co..

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