Journal article

Stereotactic Body Radiotherapy for Oligometastatic Disease in Non-small Cell Lung Cancer

Caryn Wujanto, Balamurugan Vellayappan, Shankar Siva, Alexander V Louie, Matthias Guckenberger, Ben J Slotman, Hiroshi Onishi, Yasushi Nagata, Mitchell Liu, Simon S Lo

FRONTIERS IN ONCOLOGY | FRONTIERS MEDIA SA | Published : 2019

Abstract

Metastatic non-small cell lung cancer (NSCLC) is associated with a limited survival when treated with palliative intent platinum-based chemotherapy alone. Recent advances in imaging and therapeutic strategy have identified a subset of patients with limited metastases who may benefit from early local ablative therapy with either surgery or radiotherapy, in addition to standard treatment. Stereotactic body radiotherapy (SBRT) is increasingly used in the treatment of extra-cranial oligometastatic NSCLC (OM-NSCLC) due its non-invasive conduct and ability to deliver high doses. Clinical evidence supporting the use of SBRT in OM-NSCLC is emerging and consistently demonstrates significant benefit i..

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