Journal article

Central aortic blood pressure estimation in children and adolescents: results of the KidCoreBP study

Jonathan P Mynard, Greta Goldsmith, Gabriella Springall, Lucas Eastaugh, Geoffrey K Lane, Diana Zannino, Joseph J Smolich, Alberto Avolio, Michael MH Cheung

JOURNAL OF HYPERTENSION | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

BACKGROUND: Central aortic SBP (cSBP) may have superior prognostic value compared with peripheral SBP (pSBP), but noninvasive cSBP measurement techniques have not been formally validated in children and adolescents. METHOD: This study assessed the accuracy of two automated devices and the radial tonometry/transfer function method (RT-TF) for estimating central pressures and pulse pressure amplification (PPA) in this population, with adherence to validation guidelines for central pressure devices. In 69 children/adolescents aged 3-18 years undergoing clinically indicated aortic catheterization, high fidelity ascending aortic cSBP was measured with a micromanometer-tipped wire and compared wit..

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Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by R.D. Wright Career Development Fellowship from the National Health and Medical Research Council of Australia


Awarded by National Heart Foundation of Australia


Funding Acknowledgements

This work was supported by grants from the National Health and Medical Research Council of Australia (APP1128516) and Heart Kids Australia. J.P.M. is supported by a co-funded R.D. Wright Career Development Fellowship from the National Health and Medical Research Council of Australia (APP1143510) and Future Leader Fellowship from the National Heart Foundation of Australia (101866). The Heart Research Group is supported by the Victorian Government's Operational Infrastructure Support Program, RCH 1000 and Big W.