Non-β-lactam antibiotic hypersensitivity reactions

Abstract

OBJECTIVES: Antibiotics are among the most common prescriptions in children, and non-b-lactam antibiotics (NBLAs) account for almost half of those prescribed in Australian pediatric hospitals. Despite this, data on NBLA hypersensitivity in children are limited. This study describes reported hypersensitivity reactions to NBLAs in children and the results of allergy evaluation. METHODS: Children with a suspected NBLA allergy who had skin testing and/or an intravenous or oral challenge test (OCT) between May 2011 and June 2018 were included. Patients were excluded if they were.18 years old or did not complete the allergy evaluation for any reason other than allergic reaction. RESULTS: Over the ..