Journal article

The association between atrial fibrillation and Alzheimer's disease: fact or fallacy? A systematic review and meta-analysis

Riccardo Proietti, Ahmed AlTurki, Riccardo Vio, Luca Licchelli, Francesco Rivezzi, Mariam Marafi, Vincenzo Russo, Tatjana S Potpara, Jonathan M Kalman, Etiene de Villers-Sidani, T Jared Bunch

Journal of Cardiovascular Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020

Abstract

BACKGROUND: The association between atrial fibrillation and dementia has been described. Whether a specific association exists between atrial fibrillation and Alzheimer's disease remains uncertain. This study aims to assess the association between atrial fibrillation and Alzheimer's disease through a systematic review and meta-analysis of the literature. METHODS: An exhaustive search of electronic databases up to October 2018 was conducted. Studies that identified patients with and without atrial fibrillation as well as patients with and without Alzheimer's disease and reported results of at least one relevant outcome, including hazard ratio of the association between atrial fibrillation and..

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