Journal article

An update on retinal prostheses

Lauren N Ayton, Nick Barnes, Gislin Dagnelie, Takashi Fujikado, Georges Goetz, Ralf Hornig, Bryan W Jones, Mahiul MK Muqit, Daniel L Rathbun, Katarina Stingl, James D Weiland, Matthew A Petoe



Retinal prostheses are designed to restore a basic sense of sight to people with profound vision loss. They require a relatively intact posterior visual pathway (optic nerve, lateral geniculate nucleus and visual cortex). Retinal implants are options for people with severe stages of retinal degenerative disease such as retinitis pigmentosa and age-related macular degeneration. There have now been three regulatory-approved retinal prostheses. Over five hundred patients have been implanted globally over the past 15 years. Devices generally provide an improved ability to localize high-contrast objects, navigate, and perform basic orientation tasks. Adverse events have included conjunctival eros..

View full abstract


Awarded by NHMRC Next Generation Fellowship

Awarded by NHMRC

Awarded by NIH

Awarded by Vision Core Grant

Awarded by German Ministry for Education and Research


Funding Acknowledgements

LA receives licensing royalties for purchase by commercial entities for the IVI-VLV tool and is supported by a NHMRC Next Generation Fellowship (1151055) and an NHMRC Project Grant (1082358). GD is a consultant to Second Sight Medical Products (USA), and receives licensing royalties for purchase by commercial entities for the ULV-VFQ tool. JW is a consultant to Second Sight Medical Products (USA). BJ is supported by NIH grants R01 EY015128, R01 EY028927, a P30 EY014800 Vision Core Grant and an unrestricted grant from Research to Prevent Blindness to the Moran Eye Center. RH is an employee of Pixium Vision (France). MM is a consultant to Pixium Vision (France) and receives support from the National Institute for Health Research (NIHR) London Biomedical Research Centre (BRC) at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology. MP and NB receive funding from Bionic Vision Technologies (Australia). DR is supported by the German Ministry for Education and Research, BMBF 031a308.