Microbial regulation of natural antibiotic resistance: Understanding the protist-bacteria interactions for evolution of soil resistome
Bao-Anh Thi Nguyen, Qing-Lin Chen, Ji-Zheng He, Hang-Wei Hu
Science of The Total Environment | Elsevier BV | Published : 2020
The emergence, evolution and spread of antibiotic resistance genes (ARGs) in the environment represent a global threat to human health. Our knowledge of antibiotic resistance in human-impacted ecosystems is rapidly growing with antibiotic use, organic fertilization and wastewater irrigation identified as key selection pressures. However, the importance of biological interactions, especially predation and competition, as a potential driver of antibiotic resistance in the natural environment with limited anthropogenic disturbance remains largely overlooked. Stress-affected bacteria develop resistance to maximize competition and survival, and similarly bacteria may develop resistance to fight s..View full abstract
Awarded by Australian Research Council
This work was financially supported by the Australian Research Council (DP170103628).