American Heart Association ideal cardiovascular health score and subclinical atherosclerosis in 22-35-year-old adults conceived with and without assisted reproductive technologies
Markus Juonala, Sharon Lewis, Robert McLachlan, Karin Hammarberg, Joanne Kennedy, Richard Saffery, John McBain, Liam Welsh, Michael Cheung, Lex W Doyle, David J Amor, David P Burgner, Jane Halliday
HUMAN REPRODUCTION | OXFORD UNIV PRESS | Published : 2020
STUDY QUESTION: Is ART related with the association of American Heart Association (AHA) ideal cardiovascular health score and markers of subclinical atherosclerosis? SUMMARY ANSWER: The associations between AHA score and markers of subclinical atherosclerosis in ART and non-ART groups were similar in magnitude. WHAT IS KNOWN ALREADY: Long-term consequences of ART on cardiovascular health are unknown. STUDY DESIGN, SIZE, DURATION: The study cohort for the cross-sectional analyses consisted of 172 ART-conceived and 78 non-ART conceived individuals of same age (range 22-35 years). PARTICIPANTS/MATERIALS, SETTING, METHODS: Cardiovascular risk factor status was evaluated with American Heart Assoc..View full abstract
Awarded by National Health & Medical Research Council
National Health & Medical Research Council Project Grant (APP1099641; 2016-2017); The Royal Children's Hospital Research Foundation; Monash IVF Research and Education Foundation; Reproductive Biology Unit Sperm Fund, Melbourne IVF.