Journal article

Metastatic Breast Cancer: TIL it is Too Late

Peter Savas, Sherene Loi

Clinical Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2020

Abstract

Paired analysis of primary and metastatic triple-negative breast cancers shows that metastatic disease is an immunodepleted state. This understanding has important implications for targeting the immune microenvironment in breast cancer, placing a greater emphasis on earlier stage disease and shaping future treatment strategies in the metastatic setting.See related article by Hutchinson et al., p. 657.

Grants

Funding Acknowledgements

S. Loi is supported by the National Breast Cancer Foundation of Australia Endowed Chair and the Breast Cancer Research Foundation, New York.