Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes
Charlie Jennison, Leonardo Lucantoni, Matthew T O'Neill, Robyn McConville, Sara M Erickson, Alan F Cowman, Brad E Sleebs, Vicky M Avery, Justin A Boddey
Cell Reports | CELL PRESS | Published : 2019
Awarded by NHMRC
Awarded by Cass Foundation (Science and Medicine Grant)
We thank the Australian Red Cross for the erythrocytes; Sash Lopaticki, Svenja Gunther, Annie Yang, Michelle Gazdik, and Lachlan Whitehead for technical assistance; and Matthew Dixon and Pietro Alano for the GEXP05-GFP parasites. This work was supported by NHMRC project grants (1010326 and 1049811), the Cass Foundation (Science and Medicine Grant SM/6430), Victorian State Government Operational Infrastructure Support, and Australian Government NHMRC IRIISS. A.F.C. is a Howard Hughes International Scholar, B.E.S. is an Ellen Corin Centenary Fellow, and J.A.B. is an NHMRC R.D. Wright Fellow.