Journal article
CUBN variants uncouple proteinuria from kidney function
C Quinlan
Nature Reviews Nephrology | Published : 2020
Abstract
A new study links pathogenic cubilin gene (CUBN) variants to proteinuria without progressive renal impairment, providing reassurance for a subset of patients, calling into question the accepted pathogenesis of glomerulosclerosis and suggesting future therapeutic options.
Grants
Funding Acknowledgements
The author is supported by the Royal Children's Hospital Foundation, Melbourne Genomics Health Alliance, the KidGen Collaborative and the Australian Genomics Health Alliance. The Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program.