Journal article

Reducing socio-economic inequalities in all-cause mortality: a counterfactual mediation approach

Jessica E Laine, Valeria T Baltar, Silvia Stringhini, Martina Gandini, Marc Chadeau-Hyam, Mika Kivimaki, Gianluca Severi, Vittorio Perduca, Allison M Hodge, Pierre-Antoine Dugue, Graham G Giles, Roger L Milne, Henrique Barros, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Marcel Goldberg, Marie Zins, Cyrille Delpierre Show all

International Journal of Epidemiology | OXFORD UNIV PRESS | Published : 2020

Abstract

BACKGROUND: Socio-economic inequalities in mortality are well established, yet the contribution of intermediate risk factors that may underlie these relationships remains unclear. We evaluated the role of multiple modifiable intermediate risk factors underlying socio-economic-associated mortality and quantified the potential impact of reducing early all-cause mortality by hypothetically altering socio-economic risk factors. METHODS: Data were from seven cohort studies participating in the LIFEPATH Consortium (total n = 179 090). Using both socio-economic position (SEP) (based on occupation) and education, we estimated the natural direct effect on all-cause mortality and the natural indirect ..

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Grants

Awarded by European Commission


Awarded by Medical Research Council Early Career Fellowship


Funding Acknowledgements

This work was supported by the European Commission under Horizon 2020 (grant number 633666) and J.E. Laine is supported by a Medical Research Council Early Career Fellowship (MR/M501669/1).