The incidence of hypertensive disorders of pregnancy following sperm donation in IVF: an Australian state-wide retrospective cohort study
Amber L Kennedy, Cathryn J Stern, Stephen Tong, Roxanne Hastie, Franca Agresta, Susan P Walker, Fiona C Brownfoot, Vivien MacLachlan, Beverley J Vollenhoven, Anthea C Lindquist
Human Reproduction | OXFORD UNIV PRESS | Published : 2019
STUDY QUESTION: Does IVF using donor sperm increase the risk of hypertensive disorders of pregnancy and fetal growth restriction (FGR)? SUMMARY ANSWER: IVF conceptions arising from sperm donation are not associated with an increased risk of hypertensive disorders of pregnancy or FGR. WHAT IS KNOWN ALREADY: It has been hypothesized that the absence of prior exposure to factors within the paternal ejaculate increases the risk of preeclampsia and FGR among nulliparous women or women with a new partner-the concept of 'primipaternity'. It remains unclear which element of the ejaculate is responsible: the sperm cell or the constituents of seminal fluid. IVF pregnancies arising from donor sperm whe..View full abstract
Australian Commonwealth Government-Graduate Research Scheme (to A.K.); National Health and Medical Research of Australia (salary support to S.T.); Mercy Foundation (salary support to A.L.); Department of Obstetrics and Gynaecology at the University of Melbourne (salary support to R.H.).