Journal article

The incidence of hypertensive disorders of pregnancy following sperm donation in IVF: an Australian state-wide retrospective cohort study

Amber L Kennedy, Cathryn J Stern, Stephen Tong, Roxanne Hastie, Franca Agresta, Susan P Walker, Fiona C Brownfoot, Vivien MacLachlan, Beverley J Vollenhoven, Anthea C Lindquist

Human Reproduction | OXFORD UNIV PRESS | Published : 2019

Abstract

STUDY QUESTION: Does IVF using donor sperm increase the risk of hypertensive disorders of pregnancy and fetal growth restriction (FGR)? SUMMARY ANSWER: IVF conceptions arising from sperm donation are not associated with an increased risk of hypertensive disorders of pregnancy or FGR. WHAT IS KNOWN ALREADY: It has been hypothesized that the absence of prior exposure to factors within the paternal ejaculate increases the risk of preeclampsia and FGR among nulliparous women or women with a new partner-the concept of 'primipaternity'. It remains unclear which element of the ejaculate is responsible: the sperm cell or the constituents of seminal fluid. IVF pregnancies arising from donor sperm whe..

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