Journal article

Arrhythmia recurrence is more common in females undergoing multiple catheter ablation procedures for persistent atrial fibrillation: Time to close the gender gap

Hariharan Sugumar, Shane Nanayakkara, David Chieng, Geoffrey R Wong, Ramanathan Parameswaran, Robert D Anderson, Ahmed Al-Kaisey, Chrishan J Nalliah, Sonia Azzopardi, Sandeep Prabhu, Aleksandr Voskoboinik, Geoffrey Lee, Alex J McLellan, Liang-Han Ling, Joseph B Morton, Jonathan M Kalman, Peter M Kistler

Heart Rhythm | ELSEVIER SCIENCE INC | Published : 2020

Abstract

BACKGROUND: Female gender is associated with an increased recurrence of atrial fibrillation (AF) after catheter ablation (CA). Although AF is more common in men, women constitute a significant proportion with persistent atrial fibrillation (PsAF). OBJECTIVE: The purpose of this study was to determine whether multiple ablation procedures improves arrhythmia outcomes in females with PsAF compared to men. METHODS: We performed a multicenter observational study to determine long-term arrhythmia outcomes in patients undergoing >1 CA for PsAF. CA involved pulmonary vein (PV) isolation with additional ablation including linear, posterior wall isolation, electrogram-guided, or a combination of these..

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Grants

Funding Acknowledgements

Dr Sugumar is supported by co-funded NHMRC/NHF post-graduate scholarships & RACP JJ Billings and CRE-COI scholarships. The authors have no conflicts of interest pertaining to this research. However, the following industry funding sources regarding activities outside the submitted work have been declared in accordance with ICMJE guidelines. Prof. Peter M Kistler has received funding from Abbott/St Jude Medical for consultancy and speaking engagements. Prof. JonathanMKalman has NHMRCpractitioner fellowship, research and fellowship support from Medtronic and Biosense Webster.