Co-Morbidities and Sex Differences in Long-Term Quality-of-Life Outcomes among Patients with and without Diabetes after Total Knee Replacement: Five-Year Data from Registry Study

Michelle Tew; Michelle M Dowsey; Annabelle Choong; Peter F Choong; Philip Clarke

Journal article

Co-Morbidities and Sex Differences in Long-Term Quality-of-Life Outcomes among Patients with and without Diabetes after Total Knee Replacement: Five-Year Data from Registry Study

Michelle Tew, Michelle M Dowsey, Annabelle Choong, Peter F Choong, Philip Clarke

Journal of Clinical Medicine | MDPI | Published : 2020

DOI: 10.3390/jcm9010019

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Abstract

Improved understanding of quality-of-life (QoL) outcomes can provide valuable information on intervention effectiveness and guide better patient care. The aim of this study was to examine whether QoL trajectories differ between patients with and without diabetes and identify to what extent patient characteristics are related to poor QoL outcomes after total joint replacement (TKR). Multilevel modelling was used to analyse long-term QoL patterns of patients undergoing TKR between 2006 and 2011. Patient-reported QoL at baseline and up to 5 years post-surgery were included. Of the 1553 TKR patients, one-fifth (n = 319) had diabetes. Despite there being no significant differences in QoL at basel..

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University of Melbourne Researchers

Peter Choong Author Surgery - St Vincent's Hospital

Michelle Tew Author Melbourne School of Population and Global Health

Philip Clarke Author Melbourne School of Population and Global Health

Michelle Dowsey Author Surgery - St Vincent's Hospital

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Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by National Health and Medical Research Council of Australia Career Development Fellowship

Awarded by National Health and Medical Research Council of Australia Practitioner Fellowship

Awarded by National Health and Medical Research Council Centre for Research Excellence Grant in Total Joint Replacement

Awarded by NHMRC

Awarded by Centre for Improving Cancer Outcomes Through Enhanced Infection Services

Funding Acknowledgements

This study was supported by the Australian National Health and Medical Research Council (NHMRC) funded Centre for Research Excellence in Total Joint Replacement (1116325). Michelle Dowsey holds a National Health and Medical Research Council of Australia Career Development Fellowship (1122526). Peter Choong holds a National Health and Medical Research Council of Australia Practitioner Fellowship (1154203). Peter Choong, Michelle Dowsey and Philip Clarke are recipients of a National Health and Medical Research Council Centre for Research Excellence Grant in Total Joint Replacement (1116325). Michelle Tew is jointly supported by the NHMRC funded Centre for Research Excellence in Total Joint Replacement (1116325) and Centre for Improving Cancer Outcomes Through Enhanced Infection Services (1116876), Melbourne Research Scholarship and Australian Research Council Centre of Excellence in Population Ageing Research.