Journal article

Prevalence of sarcopenia as a comorbid disease: A systematic review and meta-analysis

Jacob Pacifico, Milou AJ Geerlings, Esmee M Reijnierse, Christina Phassouliotis, Wen Kwang Lim, Andrea B Maier

Experimental Gerontology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020


BACKGROUND: Sarcopenia shares risk factors with various other age-related diseases. This meta-analysis aimed to determine the prevalence of sarcopenia as a comorbid disease. METHODS: Medline, EMBASE and Cochrane databases were searched for articles from inception to 8th June 2018, reporting the prevalence of sarcopenia in individuals with a diagnosis of cardiovascular disease (CVD), dementia, diabetes mellitus or respiratory disease and, if applicable their controls. No exclusion criteria were applied with regards to definition of sarcopenia, individuals' age, study design and setting. Meta-analyses were stratified by disease, definition of sarcopenia and continent. RESULTS: The 63 included ..

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Funding Acknowledgements

The authors would like to thank Patrick Condron (senior liaison librarian, Brownless Biomedical Library, Faculty of Medicine, Dentistry & Health Sciences, the University of Melbourne), who greatly assisted with the construction of the search strategy. This study was supported by an unrestricted grant of the University of Melbourne, Australia received by Professor Andrea B. Maier.