Journal article
Immunity-related genes and signaling pathways under hypoxic stresses in Haliotis diversicolor: a transcriptome analysis
Yulong Sun, Xin Zhang, Yilei Wang, Robert Day, Huiping Yang, Ziping Zhang
Scientific Reports | NATURE PUBLISHING GROUP | Published : 2019
Abstract
Due to increased temperatures and aquaculture density, thermal and hypoxia stresses have become serious problems for the aquaculture of abalone Haliotis diversicolor. Stresses lead to immunosuppression, which can cause severe negative impacts on aquaculture farms. To study the mechanism of immunosuppression after hypoxia stress and bacterial challenge, transcriptomes of H. diversicolor hemocytes involved in immunity were profiled. A total of 307,395,572 clean reads were generated and assembled into 99,774 unigenes. KEGG analysis indicated that 225 unigenes with immunologic function were mapped into immune-related pathways. Expression of 41 unigenes measured by quantitative real-time PCR (qRT..
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Grants
Awarded by National Key R&D Program of China
Awarded by Natural Science Foundation of China
Awarded by Special Fund for Marine Economic Development of Fujian Province
Awarded by International Science and Technology Cooperation and Communication Grant of Fujian Agriculture and Forestry University
Funding Acknowledgements
This research was funded by National Key R&D Program of China (Grant Number: 2018YFD0900304-5), the Natural Science Foundation of China (Grant Number: 41176152), Special Fund for Marine Economic Development of Fujian Province (Grant Number: ZHHY-2019-3), and International Science and Technology Cooperation and Communication Grant of Fujian Agriculture and Forestry University (Grant Number: KXGH17019).