Sustained adherence to a Mediterranean diet and physical activity on all-cause mortality in the Melbourne Collaborative Cohort Study: application of the g-formula

Elizabeth J Williamson; Julia Polak; Julie A Simpson; Graham G Giles; Dallas R English; Allison Hodge; Lyle Gurrin; Andrew B Forbes

Journal article

Sustained adherence to a Mediterranean diet and physical activity on all-cause mortality in the Melbourne Collaborative Cohort Study: application of the g-formula

Elizabeth J Williamson, Julia Polak, Julie A Simpson, Graham G Giles, Dallas R English, Allison Hodge, Lyle Gurrin, Andrew B Forbes

BMC PUBLIC HEALTH | BMC | Published : 2019

DOI: 10.1186/s12889-019-7919-2

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Abstract

BACKGROUND: Adherence to a traditional Mediterranean diet has been associated with lower mortality and cardiovascular disease risk. The relative importance of diet compared to other lifestyle factors and effects of dietary patterns over time remains unknown. METHODS: We used the parametric G-formula to account for time-dependent confounding, in order to assess the relative importance of diet compared to other lifestyle factors and effects of dietary patterns over time. We included healthy Melbourne Collaborative Cohort Study participants attending a visit during 1995-1999. Questionnaires assessed diet and physical activity at each of three study waves. Deaths were identified by linkage to na..

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University of Melbourne Researchers

Lyle Gurrin Author Melbourne School of Population and Global Health

Dallas English Author Melbourne School of Population and Global Health

Julie Simpson Author Melbourne School of Population and Global Health

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Grants

Awarded by National Health and Medical Research Council (NHMRC)

Awarded by Centre of Research Excellence grant

Awarded by NHMRC Senior Research Fellowship

Awarded by Australian National Health and Medical Research Council

Funding Acknowledgements

This work was supported by a National Health and Medical Research Council (NHMRC) project grant, ID#1004233 and a Centre of Research Excellence grant, ID#1035261, awarded to the Victorian Centre for Biostatistics (ViCBiostat). J.A. Simpson is funded by a NHMRC Senior Research Fellowship 1104975. Melbourne Collaborative Cohort Study (MCCS) recruitment was funded by VicHealth and Cancer Council Victoria. The MCCS was further supported by Australian National Health and Medical Research Council grants 209057, 251553 and 504711 and by infrastructure provided by Cancer Council Victoria. The design of the study and collection, analysis, and interpretation of data was undertaken independently of the funding bodies. None of the funders edited, or otherwise contributed to writing, the manuscript.