Prevalence of QTc Prolongation in Patients With Advanced Cancer Receiving Palliative Care-A Cause for Concern?
Janet R Hardy, Daniel Bundock, Jessica Cross, Kristen Gibbons, Ross Pinkerton, Korana Kindl, Phillip Good, Jennifer Philip
Journal of Pain and Symptom Management | ELSEVIER SCIENCE INC | Published : 2020
CONTEXT: Medications commonly used for symptom control along with other known risk factors have the potential to prolong ventricular repolarization as measured by the QT interval (the time from the start of the Q wave to the end of the T wave) on a standard electrocardiogram (ECG). OBJECTIVES: To document the prevalence of a prolonged QT interval corrected for heart rate (QTc) interval in the palliative/oncology setting, compare automatic ECG QTc measurements with manual readings and identify any correlation between QTc prolongation and the use of drugs or other risk factors. METHODS: A convenience sample of consecutive patients with cancer, admitted under or known to the palliative/supporti..View full abstract