Journal article
Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study
DN Wijeysundera, WS Beattie, GS Hillis, TEF Abbott, MA Shulman, GL Ackland, CD Mazer, PS Myles, RM Pearse, BH Cuthbertson, S Wallace, C Farrington, B Thompson, M Ellis, B Borg, RK Kerridge, J Douglas, J Brannan, J Pretto, MG Godsall Show all
British Journal of Anaesthesia | ELSEVIER SCI LTD | Published : 2020
Abstract
Background: The Duke Activity Status Index (DASI) questionnaire might help incorporate self-reported functional capacity into preoperative risk assessment. Nonetheless, prognostically important thresholds in DASI scores remain unclear. We conducted a nested cohort analysis of the Measurement of Exercise Tolerance before Surgery (METS) study to characterise the association of preoperative DASI scores with postoperative death or complications. Methods: The analysis included 1546 participants (≥40 yr of age) at an elevated cardiac risk who had inpatient noncardiac surgery. The primary outcome was 30-day death or myocardial injury. The secondary outcomes were 30-day death or myocardial infarctio..
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Awarded by Ontario Ministry of Health and Long-Term Care
Funding Acknowledgements
New Investigator Award from the Canadian Institutes of Health Research to DNW; Endowed Chair in Translational Anesthesiology Research at St Michael's Hospital and University of Toronto to DNW; Merit Awards from the Department of Anesthesia at the University of Toronto to DNW, CDM, and BHC; Medical Research Council (UK) Clinical Research Training Fellowship to TEFA; British Journal of Anaesthesia and Royal College of Anaesthetists Basic Science Career Development Award to GLA; British Oxygen Company Research Chair Grant in Anaesthesia from the Royal College of Anaesthetists to GLA; British Heart Foundation Programme Grant (RG/14/4/30736) to GLA. The METS study was supported by grants from the Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, Ontario Ministry of Health and Long-Term Care, Ontario Ministry of Research and Innovation, United Kingdom (UK) National Institute of Academic Anaesthesia, UK Clinical Research Collaboration, Australian and New Zealand College of Anaesthetists, and Monash University (Melbourne, Victoria, Australia).