Bacteria in ulcer pathogenesis

Abstract

This chapter was written at a time when Warren and Marshall had just described bacteria attached to the lining of stomach and duodenum, which they postulated were the cause of peptic ulcers. At the time, this aroused much controversy, and the chapter discussed their data and the strength of the evidence for their hypothesis. It concluded there was strong evidence the bacteria caused chronic gastritis but that more evidence was awaited regarding the claim of causing ulcers. Warren and Marshall went on to win the Nobel Prize for their work.