Overall lack of replication of associations between dietary intake of folate and vitamin B-12 and DNA methylation in peripheral blood

Pierre-Antoine Dugue; James A Chamberlain; Julie K Bassett; Allison M Hodge; Maree T Brinkman; JiHoon E Joo; Chol-Hee Jung; Ee Ming Wong; Enes Makalic; Daniel F Schmidt; John L Hopper; Daniel D Buchanan; Dallas R English; Roger L Milne; Melissa C Southey; Graham G Giles

Journal article

Overall lack of replication of associations between dietary intake of folate and vitamin B-12 and DNA methylation in peripheral blood

Pierre-Antoine Dugue, James A Chamberlain, Julie K Bassett, Allison M Hodge, Maree T Brinkman, JiHoon E Joo, Chol-Hee Jung, Ee Ming Wong, Enes Makalic, Daniel F Schmidt, John L Hopper, Daniel D Buchanan, Dallas R English, Roger L Milne, Melissa C Southey, Graham G Giles

AMERICAN JOURNAL OF CLINICAL NUTRITION | OXFORD UNIV PRESS | Published : 2020

DOI: 10.1093/ajcn/nqz253

University of Melbourne Researchers

Daniel Buchanan Author Clinical Pathology

Chol-Hee Jung Author Medicine, Dentistry and Health Sciences

John Hopper Author Melbourne School of Population and Global Health

Dallas English Author Melbourne School of Population and Global Health

Eric Ji-Hoon Joo Author Clinical Pathology

Related Projects (2)

Epidemiology of chronic disease, health interventions and DNA studies

nan

Methylation of DNA and colorectal cancer

Methylation of DNA involves a change to the chemical composition of DNA. It can affect the function of genes and normal methylation is essen..

Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

Supported by the Australian National Health and Medical Research Council (NHMRC; grant 1088405). Melbourne Collaborative Cohort Study (MCCS) cohort recruitment was funded by VicHealth and Cancer Council Victoria. The MCCS was further supported by the NHMRC (grants 396414 and 209057) and by infrastructure provided by Cancer Council Victoria. The nested case-control methylation studies were supported by the NHMRC (grants 1011618, 1026892, 1027505, 1050198, 1043616, and 1074383). MCS is an NHMRC Senior Research Fellow (1061177). DDB is a University of Melbourne Research at Melbourne Accelerator Program (R@MAP) Senior Research Fellow and NHMRC RD Wright Career Development Fellow.