The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis
Hong Min Ng, Nada Slakeski, Catherine A Butler, Paul D Veith, Yu-Yen Chen, Sze Wei Liu, Brigitte Hoffmann, Stuart G Dashper, Eric C Reynolds
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | FRONTIERS MEDIA SA | Published : 2019
Chronic periodontitis has a polymicrobial biofilm etiology and interactions between key oral bacterial species, such as Porphyromonas gingivalis and Treponema denticola contribute to disease progression. P. gingivalis and T. denticola are co-localized in subgingival plaque and have been previously shown to exhibit strong synergy in growth, biofilm formation and virulence in an animal model of disease. The motility of T. denticola, although not considered as a classic virulence factor, may be involved in synergistic biofilm development between P. gingivalis and T. denticola. We determined the role of T. denticola motility in polymicrobial biofilm development using an optimized transformation ..View full abstract
Related Projects (1)
Awarded by National Health and Medical Research Council of Australia
Awarded by Australian Government Department of Industry, Innovation and Science Grant
This research was funded by the National Health and Medical Research Council of Australia Grant ID 1083600 and the Australian Government Department of Industry, Innovation and Science Grant ID 20080108. HN was the recipient of an International Post-graduate Research Scholarship from the Australian Federal Government.