Journal article

Automatic detection of generalized paroxysmal fast activity in Lennox-Gastaut syndrome using a bi-modal EEG time-frequency feature

Amir Omidvarnia, Aaron EL Warren, Linda L Dalic, Mangor Pedersen, John S Archer, Graeme D Jackson

Cold Spring Harbor Laboratory


Objective: Mark-up of generalized interictal epileptiform discharges (IEDs) on EEG is an important step in the diagnosis and characterization of epilepsy. However, manual EEG mark-up is a time-consuming, subjective, and highly specialized task where the human reviewer needs to visually inspect a large amount of data to facilitate accurate clinical decisions. The objective of this study was to develop a framework for automated detection of generalized paroxysmal fast activity (GPFA), which is a characteristic type of generalized IED seen in scalp EEG recordings of patients with Lennox-Gastaut syndrome (LGS), a severe form of drug-resistant generalized epilepsy. Methods: We studied 13 childre..

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