Journal article

Acute severe paediatric asthma: study protocol for the development of a core outcome set, a Pediatric Emergency Reserarch Networks (PERN) study

Simon Craig, Franz E Babl, Stuart R Dalziel, Charmaine Gray, Colin Powell, Khalid Al Ansari, Mark D Lyttle, Damian Roland, Javier Benito, Roberto Velasco, Julia Hoeffe, Diana Moldovan, Graham Thompson, Suzanne Schuh, Joseph J Zorc, Maria Kwok, Prashant Mahajan, Michael D Johnson, Robert Sapien, Kajal Khanna Show all

Trials | BMC | Published : 2020


BACKGROUND: Acute severe childhood asthma is an infrequent, but potentially life-threatening emergency condition. There is a wide range of different approaches to this condition, with very little supporting evidence, leading to significant variation in practice. To improve knowledge in this area, there must first be consensus on how to conduct clinical trials, so that valid comparisons can be made between future studies. We have formed an international working group comprising paediatricians and emergency physicians from North America, Europe, Asia, the Middle East, Africa, South America, Central America, Australasia and the United Kingdom. METHODS/DESIGN: A 5-stage approach will be used: (1..

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Funding Acknowledgements

We would like to acknowledge funding from the Australasian College for Emergency Medicine Foundation, the Perth Children's Hospital Foundation, and the Emergency Medicine Foundation. The study sponsors have had no role in study design, data collection, analysis and interpretation of the data, manuscript writing, or decision to submit for publication.