Journal article

Multiple antihypertensive use and risk of mortality in residents of aged care services: a prospective cohort study

Miriam Kerry, J Simon Bell, Claire Keen, Janet K Sluggett, Jenni Ilomaki, Natali Jokanovic, Tina Cooper, Leonie Robson, Edwin CK Tan

Aging Clinical and Experimental Research | SPRINGER | Published : 2020

Abstract

AIMS: The objective of this study is to investigate the association between multiple antihypertensive use and mortality in residents with diagnosed hypertension, and whether dementia and frailty modify this association. METHODS: This is a two-year prospective cohort study of 239 residents with diagnosed hypertension receiving antihypertensive therapy across six residential aged care services in South Australia. Data were obtained from electronic medical records, medication charts and validated assessments. The primary outcome was all-cause mortality and the secondary outcome was cardiovascular-related hospitalizations. Inverse probability weighted Cox models were used to estimate hazard rati..

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