A twin study of body mass index and dental caries in childhood.
MJ Silva, NM Kilpatrick, JM Craig, DJ Manton, P Leong, H Ho, R Saffery, DP Burgner, KJ Scurrah
Scientific Reports | Nature Publishing Group | Published : 2020
Sub-optimal nutrition and dental caries are both common with significant short and long-term implications for child health and development. We applied twin statistical methods to explore the relationship between body mass index (BMI) and dental caries. We measured BMI at 18 months and six years of age and cumulative dental caries experience at six years in 344 twin children. Dental caries in primary teeth was categorised into 'any' or 'advanced' and BMI was analysed as both a continuous and categorical variable. Statistical analyses included multiple logistic regression using generalized estimating equations and within/between-pair analyses. There was no association between BMI and 'any' den..View full abstract
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We thank all twins and their families; and Tina Vaiano, Jane Loke, Anna Czajko, Chrissie Robinson, and Supriya Raj for their expertise and assistance. The research in this publication was supported by the National Institute of Dental and Craniofacial Research of the National Institutes of Health under Award Number R01DE019665. The Peri/Postnatal Epigenetic Twins Study (PETS) was supported by grants from the Australian National Health and Medical Research Council (grant numbers 437015 and 607358), the Bonnie Babes Foundation (grant number BBF20704), the Financial Markets Foundation for Children (grant number 032-2007), the Victorian Government's Operational Infrastructure Support Program, the Australian and New Zealand Society for Paediatric Dentistry Victorian Branch and The University of Melbourne Paediatric Dentistry Fund. MS was supported by an NHMRC Postgraduate Health Research Scholarship. KS is supported by a Centre of Research Excellence Grant in Twin Research and a NHMRC project grant (#1084197). DPB is supported by a NHMRC Senior Research Fellowship (APP1064629).