Journal article

Step Rate and Worsening of Patellofemoral and Tibiofemoral Joint Osteoarthritis in Women and Men: The Multicenter Osteoarthritis Study

Harvi F Hart, K Douglas Gross, Kay M Crossley, Christian J Barton, David T Felson, Ali Guermazi, Frank Roemer, Neil A Segal, Cora E Lewis, Michael C Nevitt, Joshua J Stefanik

ARTHRITIS CARE & RESEARCH | WILEY | Published : 2020

Abstract

OBJECTIVE: To determine the association of self-selected walking step rate with worsening of cartilage damage in the patellofemoral (PF) joint and tibiofemoral (TF) joint compartments at a 2-year follow-up visit. METHODS: The Multicenter Osteoarthritis Study (MOST) is a prospective cohort of men and women with or at risk of knee osteoarthritis. Self-selected step rate was measured using an instrumented GAITRite walkway (CIR Systems) at the 60-month visit. Cartilage damage was semiquantitatively graded on magnetic resonance images at the 60- and 84-month visits in the medial and lateral PF and TF compartments. Step rate was divided into quartiles, and logistic regression was used to determine..

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Grants

Awarded by NIH


Awarded by Australian Endeavour Research Fellowship


Awarded by NIH (National Institute of Arthritis and Musculoskeletal and Skin Diseases)


Awarded by NIH (National Institute of General Medical Sciences)


Funding Acknowledgements

The Multicenter Osteoarthritis Study is supported by the NIH (grants P60-AR-047785, UO1-AG-18820, UO1-AG-18832, UO1-AG-18947, and UO1-AG-19069). Dr. Hart's work was supported by an Australian Endeavour Research Fellowship (award 6603 2018). Dr. Stefanik's work was supported by the NIH (National Institute of Arthritis and Musculoskeletal and Skin Diseases grant K23-AR-070913 and National Institute of General Medical Sciences grant U54-GM-104941).