Conference Proceedings

The Effects of Phase Durations on the Spatial Responses of Retinal Ganglion Cells to Epi- and Sub-Retinal Electrical Stimulation

Wei Tong, Melanie Stamp, Maryam Hejazi, David Garrett, Steven Prawer, Michael R Ibbotson

2019 41ST ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | IEEE | Published : 2019

Abstract

Retinal prostheses have the potential to restore vision to blind patients that have retinitis pigmentosa or similar hereditary degenerative disorders, by electrically stimulating surviving retinal neurons through implanted electrode arrays. Current retinal prostheses provide limited visual acuity and one challenge is to spatially control neural activation following electrical stimulation. Most of the retinal prostheses are either epi-retinal - in front of the retinal ganglion cell layer, or sub-retinal - behind photoreceptor layer. In this study, we performed calcium imaging of ganglion cells from whole mounted retinas and compared the spread of neural activation between epi-retinal stimulat..

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