Journal article

Perfusion Computed Tomography Accurately Quantifies Collateral Flow After Acute Ischemic Stroke

Longting Lin, Chushuang Chen, Huiqiao Tian, Andrew Bivard, Neil Spratt, Christopher R Levi, Mark W Parsons

Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020


Background and Purpose- This study aimed to derive and validate an optimal collateral measurement on computed tomographic perfusion imaging for patients with acute ischemic stroke. Methods- In step 1 analysis of 22 patients, the parasagittal region of the ischemic hemisphere was divided into 6 pial arterial zones to derive the optimal collateral threshold by receiver operating characteristic analysis. The collateral threshold was then used to define the collateral index in step 2. In step 2 analysis of 156 patients, the computed tomographic perfusion collateral index was compared with collateral scores on dynamic computed tomographic angiography in predicting good clinical outcome by simple ..

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Funding Acknowledgements

Dr Lin is the recipient of Science and Industry Endowment Fund on Science, Technology, Engineering and Mathematics Business Fellowship, Australia. Dr Spratt is the recipient of Australian National Health and Medical Research Council Career Development Fellowship. Dr Parsons is funded by the National Health and Medical Research Council of Australia.