Journal article

Comparison of the effectiveness of a tailored cognitive behavioural therapy with a supportive listening intervention for depression in those newly diagnosed with multiple sclerosis (the ACTION-MS trial): protocol of an assessor-blinded, active comparator, randomised controlled trial

Litza Kiropoulos, Trevor Kilpatrick, Tomas Kalincek, Leonid Cherulov, Elizabeth McDonald, Tissa Wijeratne, Jennifer Threader, Vanja Rozenblat, Neil Simpson-O'Brien, Anneke Van der Walt, Lisa Taylor

Trials | BMC | Published : 2020

Abstract

BACKGROUND: Multiple sclerosis (MS) is an unpredictable, chronic neurological disease accompanied with high rates of depression and anxiety, particularly in the early stages of diagnosis. There is evidence to suggest that cognitive behavioural therapy (CBT) is effective for the treatment of depression amongst individuals with MS; however, there is a paucity of tailored CBT interventions designed to be offered in the newly diagnosed period. This trial is the first to assess the effectiveness and cost-effectiveness of a tailored CBT intervention compared to a supportive listening (SL) intervention amongst individuals with MS who are depressed. METHODS: ACTION-MS is a two-arm parallel group, as..

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Grants

Awarded by Multiple Sclerosis Research Australia Project Grant


Funding Acknowledgements

This work was supported by a Multiple Sclerosis Research Australia Project Grant (Grant Number 15-013). This funding source has no influence on the design of the study and has not influenced its execution, analyses, interpretation of the data or decision to submit results.