Journal article

Pelvic Exenteration for Anal and Urogenital Squamous Cell Carcinoma: Experience and Outcomes from an Exenteration Unit Over 12 Years

Nicholas Smith, Peadar S Waters, Oliver Peacock, Joseph C Kong, Jacob McCormick, Satish K Warrier, Orla McNally, Andrew C Lynch, Alexander G Heriot

ANNALS OF SURGICAL ONCOLOGY | SPRINGER | Published : 2020

Abstract

BACKGROUND: Pelvic exenteration has increasingly been shown to improve disease-free and overall survival for patients with locally advanced pelvic malignancies. Squamous cell carcinoma (SCC) is the second most common pelvic malignancy requiring exenteration. OBJECTIVE: The aim of this study was to report the clinical and oncological outcomes from patients treated with pelvic exenteration for anal and urogenital SCC from a single, high-volume unit. METHODS: A review of a prospectively maintained database from 1991 to 2018 at a high-volume specialised institution was performed. Primary endpoints included R0 resection rates, local recurrence and overall survival (OS) rates. RESULTS: From Januar..

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