Journal article
Evaluation of remission definitions for systemic lupus erythematosus: a prospective cohort study
V Golder, R Kandane-Rathnayake, M Huq, W Louthrenoo, SF Luo, YJJ Wu, A Lateef, S Sockalingam, SV Navarra, L Zamora, L Hamijoyo, Y Katsumata, M Harigai, M Chan, S O'Neill, F Goldblatt, CS Lau, ZG Li, A Hoi, M Nikpour Show all
Lancet Rheumatology | ELSEVIER | Published : 2019
Abstract
Background: Validated outcome measures are needed from which to derive treatment strategies for systemic lupus erythematosus (SLE). However, no definition of remission for SLE has been widely adopted. The Definitions of Remission in Systemic Lupus Erythematosus (DORIS) group has proposed a framework with multiple potential definitions of remission. In this study, we aimed to assess the attainability and effect on disease outcomes of the DORIS definitions of remission, compared with the lupus low disease activity state (LLDAS), in patients with SLE. Methods: In this prospective cohort study, we enrolled patients with SLE from 13 international centres that are part of the Asia Pacific Lupus Co..
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Funding Acknowledgements
UCB, GlaxoSmithKline, Janssen, Bristol-Myers Squibb, and AstraZeneca.