Journal article
A multi-national, multi-disciplinary Delphi consensus study on using omega-3 polyunsaturated fatty acids (n-3 PUFAs) for the treatment of major depressive disorder
Ta-Wei Guu, David Mischoulon, Jerome Sarris, Joseph Hibbeln, Robert K McNamara, Kei Hamazaki, Marlene P Freeman, Michael Maes, Yutaka J Matsuoka, RH Belmaker, Wolfgang Marx, Carmine Pariante, Michael Berk, Felice Jacka, Kuan-Pin Su
Journal of Affective Disorders | ELSEVIER | Published : 2020
Abstract
INTRODUCTION: Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are recommended as an integrative treatment for major depressive disorder (MDD). In 2019, the International Society for Nutritional Psychiatry Research (ISNPR) developed the first practice guidelines for n-3 PUFA treatment of MDD. To strengthen these guidelines and enhance their clinical applicability, we synthesized the evidence and clinical experiences previously obtained through the Delphi methodology. METHODS: Nineteen statements covering five major domains in MDD treatment were formulated through internal meetings. Fourteen international experts were invited to participate in the web-based Delphi process that validated the st..
View full abstractGrants
Awarded by Ministry of Science and Technology, Taiwan
Awarded by National Health Research Institutes, Taiwan
Awarded by Higher Education Sprout Project by the Ministry of Education (MOE), Taiwan
Awarded by China Medical University, Taichung, Taiwan
Awarded by China Medical University Hospital, Taichung, Taiwan
Awarded by NHMRC Senior Principal Research Fellowship
Awarded by NHMRC Clinical Research Fellowship
Awarded by University of Macau, China
Funding Acknowledgements
The authors of this work were supported by the following grants: MOST 108-2320-B-039-048; 108-2314-B-039-016; MOST 108-2813-C-039-133-B; 106-2314-B-039-027-MY3; and 106-2314-B-039-027 from the Ministry of Science and Technology, Taiwan; NHRI-EX108-10528NI from the National Health Research Institutes, Taiwan; CMRCCMA-3 from Higher Education Sprout Project by the Ministry of Education (MOE), Taiwan; CMU108-SR-106 from the China Medical University, Taichung, Taiwan; and CRS-108-048, DMR-108-216 and DMR-109-102 from the China Medical University Hospital, Taichung, Taiwan. In addition, Michael Berk is supported by a NHMRC Senior Principal Research Fellowship (1059660 and APP1156072) and Jerome Sarris is supported by an NHMRC Clinical Research Fellowship (APP1125000). We thank Miss Yu-Chuan Chien from University of Macau, China (MYRG2018-00242-ICMS) for data collection and organization.