Journal article
A multi-national, multi-disciplinary Delphi consensus study on using omega-3 polyunsaturated fatty acids (n-3 PUFAs) for the treatment of major depressive disorder
TW Guu, D Mischoulon, J Sarris, J Hibbeln, RK McNamara, K Hamazaki, MP Freeman, M Maes, YJ Matsuoka, RH Belmaker, W Marx, C Pariante, M Berk, F Jacka, KP Su
Journal of Affective Disorders | ELSEVIER | Published : 2020
Abstract
Introduction: Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are recommended as an integrative treatment for major depressive disorder (MDD). In 2019, the International Society for Nutritional Psychiatry Research (ISNPR) developed the first practice guidelines for n-3 PUFA treatment of MDD. To strengthen these guidelines and enhance their clinical applicability, we synthesized the evidence and clinical experiences previously obtained through the Delphi methodology. Methods: Nineteen statements covering five major domains in MDD treatment were formulated through internal meetings. Fourteen international experts were invited to participate in the web-based Delphi process that validated the st..
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Awarded by Wilson Foundation
Funding Acknowledgements
The authors of this work were supported by the following grants: MOST 108-2320-B-039-048; 108-2314-B-039-016; MOST 108-2813-C-039-133-B; 106-2314-B-039-027-MY3; and 106-2314-B-039-027 from the Ministry of Science and Technology, Taiwan; NHRI-EX108-10528NI from the National Health Research Institutes, Taiwan; CMRCCMA-3 from Higher Education Sprout Project by the Ministry of Education (MOE), Taiwan; CMU108-SR-106 from the China Medical University, Taichung, Taiwan; and CRS-108-048, DMR-108-216 and DMR-109-102 from the China Medical University Hospital, Taichung, Taiwan. In addition, Michael Berk is supported by a NHMRC Senior Principal Research Fellowship (1059660 and APP1156072) and Jerome Sarris is supported by an NHMRC Clinical Research Fellowship (APP1125000). We thank Miss Yu-Chuan Chien from University of Macau, China (MYRG2018-00242-ICMS) for data collection and organization.