The distinctive neural circuitry of complex posttraumatic stress disorder during threat processing
Richard A Bryant, Kim L Felmingham, Gin Malhi, Elpiniki Andrew, Mayuresh S Korgaonkar
PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2021
BACKGROUND: There is controversy over the extent to which the new International Classification of Diseases (ICD-11) diagnosis of complex posttraumatic stress disorder (CPTSD) is distinct from posttraumatic stress disorder (PTSD). This study aimed to conduct the first investigation of distinctive neural processes during threat processing in CPTSD relative to PTSD. METHOD: This cross-sectional functional magnetic resonance study included 99 participants who met criteria for PTSD (PTSD = 32, CPTSD = 28) and 39 trauma-exposed controls. PTSD was assessed with the Clinician-Administered PTSD Scale (CAPS). CPTSD was assessed with an adapted version of the International Trauma Questionnaire. Neural ..View full abstract
Awarded by National Health and Medical Research Council
The study was funded by the National Health and Medical Research Council (1073041). The funder had no role in study design, data collection or analysis, or report preparation.