Journal article

CORP: Practical tools for improving experimental design and reporting of laboratory studies of cardiovascular physiology and metabolism

Kate L Weeks, Darren C Henstridge, Agus Salim, Jonathan E Shaw, Thomas H Marwick, Julie R McMullen

American Journal of Physiology-Heart and Circulatory Physiology | AMER PHYSIOLOGICAL SOC | Published : 2019


The exercise consisted of: 1) a short survey to acquire baseline data on current practices regarding the conduct of animal studies, 2) a series of presentations for promoting awareness and providing advice and practical tools for improving experimental design, and 3) a follow-up survey 12 mo later to assess whether practices had changed. The surveys were compulsory for responsible investigators (n = 16; paired data presented). Other investigators named on animal ethics applications were encouraged to participate (2017, total of 36 investigators; 2018, 37 investigators). The major findings to come from the exercise included 1) a willingness of investigators to make changes when provided with ..

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Funding Acknowledgements

This work was supported by the Victorian Government's Operational Infrastructure Support Program. J. R. McMullen and J. E. Shaw are National Health and Medical Research Council Fellows (IDs APP1079438, APP1078985). K.L. Weeks and D. C. Henstridge are supported by an Emerging Leader Fellowship and Baker Fellowship, respectively, from The Shine On Foundation and the Baker Heart and Diabetes Institute.