Journal article

Left Atrial Mechanical Dispersion Assessed by Strain Echocardiography as an Independent Predictor of New-Onset Atrial Fibrillation: A Case-Control Study

Hiroshi Kawakami, Satish Ramkumar, Mark Nolan, Leah Wright, Hong Yang, Kazuaki Negishi, Thomas H Marwick

Journal of the American Society of Echocardiography | MOSBY-ELSEVIER | Published : 2019


BACKGROUND: Left atrial (LA) enlargement is associated with atrial fibrillation (AF), but new-onset AF often occurs in the absence of LA enlargement. AF may be related to myocardial fibrosis, and even though left ventricular fibrosis is associated with mechanical dispersion, this phenomenon is not well studied in AF. We hypothesized that detection of LA dysfunction and mechanical dispersion using strain echocardiography is useful for predicting new-onset AF. METHODS: Baseline echocardiography was performed at entry in 576 community-based participants at risk of heart failure or AF. In this case-control study, we compared 35 individuals with new-onset AF (age 70 ± 4 years; 57% men) over 2 yea..

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Awarded by National Health and Medical Research Council, Canberra

Funding Acknowledgements

This work was partially supported by a Partnership grant (1149692) from the National Health and Medical Research Council, Canberra, the Tasmanian Community Fund, Hobart, and the Baker Heart and Diabetes Institute.