Left atrial booster pump function is an independent predictor of subsequent life-threatening ventricular arrhythmias in non-ischaemic cardiomyopathy
Kazuaki Negishi, Tomoko Negishi, Omeed Zardkoohi, Elizabeth A Ching, Nivedita Basu, Bruce L Wilkoff, Zoran B Popovic, Thomas H Marwick
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING | OXFORD UNIV PRESS | Published : 2016
AIMS: Left atrial (LA) function helps to preserve cardiac output and to control pulmonary capillary wedge pressure in the setting of left ventricular (LV) impairment, but little is known about the contribution of the LA function to ventricular arrhythmia. We sought whether LA booster pump function was associated with arrhythmias in patients undergoing primary prevention implantable cardioverter-defibrillator (ICD) implantation for non-ischaemic dilated cardiomyopathy (NICM), independent of global longitudinal strain (GLS) and mechanical dispersion (MD). METHODS AND RESULTS: We identified 124 NICM patients (56 ± 13, 67 male) who underwent echocardiography pre-ICD implantation for primary prev..View full abstract
K.N. is supported by an award from the Select Foundation, which had no role for the preparation of this manuscript. T.H.M. received research support from GE, Philips and Siemens.