Journal article

Myocardial blood volume and perfusion reserve responses to combined dipyridamole and exercise stress: A quantitative approach to contrast stress echocardiography

S Moir, BA Haluska, C Jenkins, D McNab, TH Marwick

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY | MOSBY-ELSEVIER | Published : 2005

Abstract

BACKGROUND: Qualitative interpretation of myocardial contrast echocardiography (MCE) improves the accuracy of wall-motion analysis for assessment of coronary artery disease (CAD). We examined the feasibility and accuracy of quantitative MCE for diagnosis of CAD. METHODS: Dipyridamole/exercise stress MCE (destruction-replenishment protocol with real-time imaging) was performed in 90 patients undergoing quantitative coronary angiography, 48 of whom had significant (> 50%) stenoses. MCE was repeated with exercise alone in 18 patients. Myocardial blood flow (A*beta) was obtained from blood volume (A) and time to refill (beta). RESULTS: Quantification of flow reserve was feasible in 88%. The mean..

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