Journal article

Is there a role for diastolic function assessment in era of delayed enhancement cardiac magnetic resonance imaging? A multimodality imaging study in patients with advanced ischemic cardiomyopathy

Joao L Cavalcante, Thomas H Marwick, Rory Hachamovitch, Zoran B Popovic, Nael Aldweib, Randall C Starling, Milind Y Desai, Scott D Flamm, Deborah H Kwon



UNLABELLED: Cardiac magnetic resonance (CMR) identifies important prognostic variables in ischemic cardiomyopathy (ICM) patients such as left ventricular (LV) volumes, LV ejection fraction (LVEF), peri-infarct zone, and myocardial scar burden (MSB). It is unknown whether Doppler-based diastolic dysfunction (DDF) retains its prognostic value in ICM patients, in the context of current imaging, medical, and device therapies. METHODS: Diastolic function was evaluated in ICM patients (LVEF ≤ 40% and ≥ 70% stenosis in ≥ 1 coronary artery) who underwent transthoracic echocardiogram and delayed hyperenhancement CMR studies within 7 days. The association of DDF with the combined end point was assesse..

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