Quantitation of the diastolic stress test: Filling pressure vs. diastolic reserve

Abstract

AimsThe diastolic stress test (DST) may facilitate the attribution of exertional dyspnoea to cardiac and non-cardiac diseases. However, there is currently no consensus as to the optimal marker of exertional diastolic dysfunction (DD)-the main alternatives being estimated left ventricular (LV) filling pressure (exercise E/e′) and diastolic functional reserve (DFRI). We sought to compare the correlates of these parameters.Methods and resultsDST was performed by adding the measurement of the transmitral (E) and annular (e′) velocities to standard exercise echo in 559 consecutive patients without significant rest or exercise mitral regurgitation. Exertional DD was separately defined by post-stre..