Effects of Exercise and Lifestyle Intervention on Cardiovascular Function in CKD
Erin J Howden, Rodel Leano, William Petchey, Jeff S Coombes, Nicole M Isbel, Thomas H Marwick
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | AMER SOC NEPHROLOGY | Published : 2013
BACKGROUND AND OBJECTIVES: CKD is associated with poor cardiorespiratory fitness (CRF). This predefined substudy determined the effect of exercise training and lifestyle intervention on CRF and explored the effect on cardiovascular risk factors and cardiac and vascular function. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Between February 2008 and March 2010, 90 patients with stage 3-4 CKD were screened with an exercise stress echocardiogram before enrollment. Patients (n=83) were randomized to standard care (control) or lifestyle intervention. The lifestyle intervention included multidisciplinary care (CKD clinic), a lifestyle program, and aerobic and resistance exercise training for 12 ..View full abstract
This research was supported by the National Health and Medical Research Council-funded Centre for Clinical Research Excellence-Vascular and Metabolic Health of the University of Queensland, as well as the Department of Nephrology at Princess Alexandra Hospital.