Journal article
Arterial stiffness, central blood pressure and body size in health and disease
OO Kolade, TM O'Moore-Sullivan, M Stowasser, JS Coombes, RG Fassett, TH Marwick, JE Sharman
International Journal of Obesity | NATURE PUBLISHING GROUP | Published : 2012
DOI: 10.1038/ijo.2011.79
Abstract
Background:Body size is associated with increased brachial systolic blood pressure (SBP) and aortic stiffness. The aims of this study were to determine the relationships between central SBP and body size (determined by body mass index (BMI), waist circumference and waisthip ratio) in health and disease. We also sought to determine if aortic stiffness was correlated with body size, independent of BP.Methods:BMI, brachial BP and estimated central SBP (by SphygmoCor and radial P2) were recorded in controls (n=228), patients with diabetes (n=211), coronary artery disease (n=184) and end-stage kidney disease (n68). Additional measures of waist circumference and arterial stiffness (aortic and brac..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
The source of support is as follows: Dr Sharman is supported by a Career Development Award from the National Health and Medical Research Council of Australia (reference 569519).